United Kingdom
The Netherlands, Switzerland, Austria, Italy, Sweden, Denmark, France, Poland
Israel, Greece

Old Antibiotics Course

Improving the Dosage of Old Antibiotics

AIDA together with the ESCMID PK/PD of Anti-Infectives Study Group (EPASG) organises and presents the Postgraduate Education Course on Improving the Dosage of Old Antibiotics on 19-21 November 2015 in Warsaw, Poland.

Course Objectives: This course presents and summarizes currently available knowledge regarding optimized clinical use of revived old antibiotics such as colistin, fosfomycin, temocillin, pivmecillinam, nitrofurantoin, fusidic acid, minocycline. The aim is to provide participants with an updated insight into clinical PK/PD concepts, improved dosage regimens, combinations, appropriate indications as a
key contribution to preserving the efficacy of these essential drugs in an era of escalating multi-drug resistance.

Course Venue: Hotel Bristol
Krakowskie Przedmiescie 42/44
00325 Warsaw, Poland

Faculty Members:

Karen Bowker, Bristol, United Kingdom Angela Huttner, Geneva, Switzerland
Yehuda Carmeli, Tel Aviv, Israel Leonard Leibovici, Petah-Tiqva, Israel
William Couet, Poitiers, France Alasdair MacGowan, Bristol, United Kingdom
Lena Friberg, Uppsala, Sweden Johan Mouton, Rotterdam, Netherlands
Niels Frimodt-Möller, Copenhagen, Denmark                    Anouk Muller, The Hague, Netherlands
Maciek Godycki-Cwirko, Lodz, Poland Mical Paul, Haifa, Israel
William Hope, Liverpool, United Kingdom Ursula Theuretzbacher, Vienna, Austria

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Thursday, 19 November 2015

14:30-15:00 Welcome and introduction Ursula Theuretzbacher
15.00-15.30 Why do we need to revive old antibiotics? Ursula Theuretzbacher
15.30-16.30 Basics of optimal dosing Johan Mouton
16.30-17.00 Break
17.00-19.00 Dosing considerations for old antibiotics (e.g. colistin) and therapeutic drug monitoring Lena Friberg & William Couet
19.30 Dinner

Friday, 20 November 2015

9.00-9.30 Emergence of resistance in individual patients Yehuda Carmeli
9.30-10.00 Safety concerns and their relation to dosing Alasdair MacGowan
10.00-10.30 Reviving old antibiotics: the AIDA experience-preserving old antibiotics for the future Ursula Theuretzbacher
10.30-11.00 Coffee break
11.00-11.45 Integration of dosing into stewardship programmes (interactive) Mical Paul
11.45-13.00 Interpretation of clinical trial results (clinical case studies, interactive) Mical Paul, Leonard Leibovici
13.00 Lunch
14:00-14.30 What do we know about nitrofurantoin? Anouk Muller
14:30-15.00 What do we know about fosfomycin? Angela Huttner
15:00-15.30 What do we know about minocyclin? Karen Bowker
15:30-16.00 Break
16:00-17:30 How to optimize the use of oral antibiotics: nitrofurantoin, fosfomycin-trometamol, mecillinam, rifampicin, minocycline and other antibiotics (clinical case studies, interactive). A. Muller, W. Hope, N. Frimodt-Möller, A. Huttner, A. MacGowan & M. Godycki-Cwirko
17:30 Quiz with A. Muller, W. Hope, N. Frimodt-Möller, A. Hutter, A. MacGowan, M. Godycki-Cwirko
19:30 Dinner

Saturday, 21 November 2015

9:00-9:40 The clinical use of colistin: past, present, future Mical Paul
09:40-10:20 How to set breakpoints of old antibiotics: the EUCAST approach (interactive) MacGowan
10:20-11:00 Dosing in special patient populations William Hope
11:00-11:30 Break
11:30-12:30 Tools to support dosing decisions (case presentation, interactive) William Hope
12:30-13:30 How to optimize the use of i.v. antibiotics: Colistin, ß-lactams and other old antibiotics (clinical case studies, interactive). William Couet, Alasdair MacGowan
13:30 Closure
13:35 Lunch