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Colistin presentations

Population pharmacokinetics of colistin methanesulfonate (CMS) and colistin in critically ill patients receiving intermittent haemodialysis

N. Grégoire, B. Mégarbane, E. Comets, P. Gobin, D. Balayn, O. Mimoz, W. Couet (Poitiers, Paris, FR). ECCMID 2013, 30 April 2013,
Abstract (oral session): Old drugs, new challenges - PK/PD for glycopeptides and polymyxins

Whole-body physiologically-based pharmacokinetic model for colistin and colistimethate sodium (CMS) in five different animal species: mouse, rat, rabbit, baboon and pig

S. Bouchene*, S. Marchand, L.E. Friberg, S. Björkman, W. Couet, M.O. Karlsson (Uppsala, SE; Poitiers, FR). ECCMIDl 2013, Abstract (poster session), PK/PD: new drugs, the critically and resistant bugs

Nephrotoxicity of colistin and role of kidney disease on patient outcomes in infections due to extensively-drug resistant Acinetobacter baumannii

R. Andini, E. Durante Mangoni*, A. Senese, D. Pinto, F. Agrusta, I. Mattucci, V. Farinaro, C. Graziano, C. Battimelli, C. Savinelli, V. Iorio, M. Bassetti, P. Malacarne, N. Petrosillo, C. Viscoli, R. Utili (Naples, Genoa, Pisa, Rome, IT). ECCMID 2013, Abstract (oral session),
Old drugs, new challenges - PK/PD for glycopeptides and polymyxins

Comparison of colistin-carbapenem, colistin-sulbactam and colistin-other antibacterial agent for treatment of multidrug-resistant Acinetobacter bacteraemia: a multicentre retrospective study

A. Batirel, I.I. Balkan, O. Karabay, C. Agalar, S. Akalin, O. Alici, F.A. Altay, N. Altin, F. Arslan, T. Aslan, N. Bekiroglu, S. Cesur, A.D. Celik, M. Dogan, B. Durdu, F. Duygu, A. Engin, D.O. Engin, I. Gonen, E. Guclu, T. Guven, C.A. Hatipoglu, S. Hosoglu, M.K. Karahocagil, A. Ulu Kilic, E. Alp Mese, B. Ormen, D. Ozdemir, S. Ozer, N. Oztoprak, N. Sezak, V. Turhan, N. Turker, H. Yilmaz (Istanbul, Sakarya, Denizli, Ankara, Edirne, Tekirdag, Tokat, Sivas, Isparta, Diyarbakir, Van, Kayseri, Izmir, Duzce, Antalya, Samsun, TR). ECCMID 2013, Abstract (oral session), Evolving therapeutic strategies for serious infections

Monotherapy versus combination treatment against multidrug-resistant (MDR) Acinetobacter baumannii infection. Study GEIH/REIPI-Ab 2010

L.E. López-Cortés*, J. Rodríguez-Baño, A. Pascual, G. Bou Arevalo, M. Tomás-Carmona, J. Garnacho, F. Fernández-Cuenca, L. Martínez-Martínez, J. Vila, J. Pachón, J.M. Cisneros on behalf of the GEIH-REIPI-Ab 2010 working group. ECCMID 2013, Abstract (oral session),
Evolving therapeutic strategies for serious infections

The pharmacokinetic index Css is not a predictor of mortality among patients with infections caused by multidrug-resistant Gram-negative bacteria treated with colistin

L. Sorlí*, S. Luque, S. Grau, N. Campillo, M. Montero, F. Alvarez-Lerma, C. Segura, H. Knobel, J. Horcajada (Barcelona, ES). ECCMID 2013, Abstract (publication only), Antimicrobial pharmacokinetics, pharmacodynamics, pharmacogenomics, pharmacoeconomics and general pharmacology

Pharmacokinetics of colistin after the administration of two different loading doses (4.5 MU or 6 MU) of colistin methanesulfonate in critically ill patients

F. Docobo-Pérez*, A. Gutiérrez-Valencia, A. Gutiérrez-Pizarraya, J. Domínguez-Herrera, S. Luque, J. Garnacho-Montero, J.A. Márquez-Vácaro, A. Puppo, C. Rosso, P. Moreno-Martínez, C. Milara-Ibáñez, J. Pachón, J.M. Cisneros-Herreros (Seville, Barcelona, ES). ECCMID 2013, Abstract (publication only), Antimicrobial pharmacokinetics, pharmacodynamics, pharmacogenomics, pharmacoeconomics and general pharmacology

Nephrotoxicity associated with colistin therapy: a comparative analysis of older and younger adults

J.M. Pogue, K.S. Kaye (Detroit, US), ECCMID 2013, Abstract (poster session), Endocarditis and other serious infections - Clinical observations

Colistin-associated nephrotoxicity in two large Korean hospitals; incidence and predictors for nephrotoxicity

YS. Park*, EW. Kang, H. Ro, JY. Jung, HH. Lee, W. Chung, TI. Chang, JH. Chang (Incheon, Koyang, KR). ECCMID 2013, Abstract (publication only), Antibiotic usage

Underdosed colistin prescription in patients with multi-resistant Gram-negative bloodstream infections

D. Ripamonti*, G. Masini, E. Bombana, A. Grigis, A. Raglio, M. Rizzi (Bergamo, IT). ECCMID 2012, Abstract (poster session), Clinical experience with antibiotics

Interest of therapeutic drug monitoring for the management of Colistin IV QD treatment for Pseudomonas aeruginosa pulmonary infection in cystic fibrosis lung transplantation

R. Guillemain, V. Poinsignon, C. Woloch, C. Amrein, V. Boussaud, E. Carbonnelle, E.M. Billaud* (Paris, FR). ECCMID2013, Abstract (poster session), Infections in transplant and immunodeficiency patients

Klebsiella pneumoniae carbapenemase (KPC)-producing Klebsiella pneumoniae resistant to colistin: epidemiology and risk factors for colonisation during intensive care unit stay

M. Papadimitriou-Olivgeris*, C. Bartzavali, F. Fligou, C. Sklavou, S. Vamvakopoulou, M. Christofidou, K. Filos, M. Marangos, E. Anastassiou (Patras, GR). ECCMID 2013, Abstract (oral session), Impact of human behaviour on drug resistance and vice versa

Colistin-heteroresistance in Klebsiella pneumoniae carbapenemase (KPC)-producing Klebsiella pneumoniae: from inducible resistance to stable resistance

A. Vecchione, B. Casini, P. Valentini, E. Tagliaferri, C. Tascini*, F. Menichetti, G. Privitera (Pisa, IT). ECCMID 2013, Abstract (poster session), Molecular bases of antimicrobial resistance in Enterobacteriaceae

Biological cost of colistin-resistance in clinical isolates of Acinetobacter baumannii

E.J. Yoon, P. McGann, E. Lesho, P. Waterman, R. Clifford, P. Courvalin, C. Grillot-Courvalin* (Paris, FR; Silver Spring, US). ECCMID 2013, Abstract (poster session), Resistance mechanisms and their detection in MDR Acinetobacter

Risk factors and mortality of bloodstream infections due to colistin-resistant, carbapenem-resistant Klebsiella pneumoniae in a teaching hospital in Italy. Comparison with colistin-susceptible strains

V. Del Bono*, D.R. Giacobbe, G. Orengo, C. Saffioti, A. Parisini, A. Marchese, S. Reggiani, L. Taramasso, D. Zoli, P. Durando, C. Viscoli (Genova, IT). ECCMID 2013, Abstract (poster session), Bloodstream infections caused by MDR Gram-negatives

Colistin-resistance in Gram-negative bacilli

Jordi Villa, Barcelona, Spain. ECCMID 2013, Symposium Resistance to non-beta-lactam antibiotics in Gram-negative bacilli

Activity of colistin (Col) alone and in combination with doripenem (Dor) at clinically-achievable concentrations against Pseudomonas aeruginosa (PA) in an in vitro dynamic biofilm model

J. Lora-Tamayo*, O. Murillo, J. Jacob, J. Ariza, R.L. Nation, J. Li (Barcelona, ES; Melbourne, AU). ECCMID 2013, Abstract (poster session), Biofilms

Worldwide colistin and polymixin usage, the "last" Gram-negative antibiotics: results from an online global survey

H. Wertheim* (Hanoi, VN). ECCMIDl 2012, Abstract (poster session), Clinical experience with antibiotics